September 1, 2022

Aeon Respire's Patent-Protected AR-001 Inhalation Formulation Achieves Lung Exposure 1000 Times Higher Than Oral Delivery

Aeon Respire is pleased to announce that they’ve completed a pivotal pharmacokinetic (PK) study with inhalation delivery of their lead drug AR-001. Inhaled AR-001 led to 1000 times higher lung exposure than

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June 9, 2022

Aeon Respire Presents at the 2022 Biotechnology Innovation Organization (Bio) Convention

We are pleased to announce that Aeon Respire has been selected to present at the 2022 BIO International Convention in San Diego. Dirk Smith, VP of R&D, will present on Monday June 13th at 3:45 pm.

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February 10, 2022

Scientists Identify the Molecular Binding Site of the Drug Niclosamide on TMEM16 PROTEINS

Scientists at the University of California, San Francisco identify the molecular binding site of niclosamide on TMEM16 by high resolution cryo-electron microscopy.

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January 1, 2022

Aeon Respire is Awarded Phase 2 Extension Funding From NIH Fast Track SBIR Award

Aeon Respire has been awarded Phase 2 extension SBIR funding from the NIH. This award was contingent on Aeon Respire successfully completing all required dry powder formulation milestones during the Phase 1 period of the SBIR Fast-Track grant

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December 8, 2021

Aeon Respire & CritiTech Enter into Strategic Partnership

Aeon Respire is pleased to announce that it has entered into a strategic drug development collaboration and licensing agreement with CritiTech Particle Engineering Solutions of Lawrence, Kansas (”CritiTech”).

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April 7, 2021

Drugs that Inhibit TMEM16 Block COVID-19 Virus

Drugs that inhibit TMEM16 proteins block SARS-CoV-2 spike protein-induced syncytia formation in the lung leading to lymphocyte depletion and COVID-19 disease pathogenesis. Niclosamide was reported in 2020 by several laboratories as a potent inhibitor of SARS-CoV-2 virus replication.

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September 10, 2019

Ex-Amgen Respiratory Scientists Form New Company

Ex-Amgen leaders in respiratory disease form new company Aeon Respire, Inc., based on their pivotal discovery reported in Frontiers in Pharmacology. They found that the approved drugs niclosamide and nitazoxanide are potent inhibitors of the calcium-activated chloride channel TMEM16A that fully bronchodilate human airways.

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